State-of-the-art reviews covering major aspects of antibodies and intervention against infectious diseases
The connection between antibodies and infectious diseases has spawned entire related fields of study. Antibodies for Infectious Diseases presents perspectives from leading research scientists and summarizes the amazing progress in this area into a single definitive source.
Providing a broad survey of the most important aspects of the field of antibodies for infectious diseases, this book
- presents general features pertaining to structure, function, isotype, and the role of complement in antibody function
- examines the role of antibodies in antimicrobial immunity with specific targets
- details new methods for expression of monoclonal antibodies, in plants or by transfer of antibody genes for in vivo expression in treated subjects
Antibodies for Infectious Diseases is a comprehensive reference for researchers, pharmaceutical developers, and health care professionals on the status of the development of antibody-based therapies for treating infectious diseases. It is also useful as supplemental reading for upper level life sciences students.
About the Author
James E. Crowe, Jr. is an immunologist and board-certified pediatric infectious diseases specialist. Dr. Crowe is the Ann Scott Carell Chair and Professor of Pediatrics, Pathology, Microbiology and Immunology, and Director of the Vanderbilt Vaccine Center. He is an Elected Member of the Institute of Medicine and a Fellow of the American Association for the Advancement of Science, the American Academy of Microbiology, and the American Society for Clinical Investigation.
Diana Boraschi is the Research Director at the CNR Institute of Protein Biochemistry. She is actively involved in high education activities, in particular in Africa.
Rino Rappuoli is the Global Head of Research and Development at Novartis Vaccines. Dr. Rappuoli has worked on several molecules that became part of, or are near to becoming, licensed vaccines. He is an elected member of the U.S. National Academy of Sciences and of the European Molecular Biology Organization.